Pathophysiology of Sleep Apnea
نویسندگان
چکیده
منابع مشابه
Pathophysiology of sleep apnea.
Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence of an anatomically compromised, collapsible airway, the sleep-induced loss of compensatory tonic input to the upper airway dilator muscle motor neurons leads to collapse of the pharyngeal airway. In turn, the a...
متن کاملPathophysiology of adult obstructive sleep apnea.
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive narrowing or collapse of the pharyngeal airway during sleep. The disorder is associated with major comorbidities including excessive daytime sleepiness and increased risk of cardiovascular disease. The underlying pathophysiology is multifactorial and may vary considerably between individuals. Important risk factors i...
متن کاملPathophysiology of pediatric obstructive sleep apnea.
Sleep-disordered breathing is a common and serious cause of metabolic, cardiovascular, and neurocognitive morbidity in children. The spectrum of obstructive sleep-disordered breathing ranges from habitual snoring to partial or complete airway obstruction, termed obstructive sleep apnea (OSA). Breathing patterns due to airway narrowing are highly variable, including obstructive cycling, increase...
متن کاملPhysiology and Pathophysiology of Sleep Apnea Beyond the Fat Boy: the intertwining pathophysiologies of sleep apnea
Over the past 20 years, increasing data have accumulated underscoring the public health importance of sleep apnea with growing evidence of its high prevalence and myriad clinical manifestations. This condition, rarely diagnosed in the past, had been considered to occur predominantly as a manifestation of morbid obesity and considered to affect almost exclusively middle-aged men. Sleepiness and ...
متن کاملInvited Review HIGHLIGHTED TOPIC Physiology and Pathophysiology of Sleep Apnea Pathogenesis of obstructive sleep apnea
Ryan, Clodagh M., and T. Douglas Bradley. Pathogenesis of obstructive sleep apnea. J Appl Physiol 99: 2440-2450, 2005; doi:10.1152/japplphysiol.00772.2005.— The pathogenesis of obstructive sleep apnea (OSA) has been under investigation for over 25 years, during which a number of factors that contribute to upper airway (UA) collapse during sleep have been identified. Structural/anatomic factors ...
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ژورنال
عنوان ژورنال: Physiological Reviews
سال: 2010
ISSN: 0031-9333,1522-1210
DOI: 10.1152/physrev.00043.2008